CMS to Test Prior Authorization Model in Traditional Medicare
(MedPage Today) — The Centers for Medicare & Medicaid Services (CMS) announced a new experimental model late last week to […]
JAK Inhibitors’ Cancer Risk Confirmed in Real-World Data
(MedPage Today) — Use of Janus kinase (JAK) inhibitors for rheumatoid arthritis (RA) was associated with significantly higher rates of
NEJM
Case 18-2025: A 63-Year-Old Woman with Dyspnea on Exertion
A 63-year-old woman was evaluated for dyspnea and edema. Soft-tissue thickening was noted in the retroperitoneum and mediastinum and around
Rheumato
Rheumato, Vol. 5, Pages 8: Unlocking the Secrets of Knee Joint Unloading: A Systematic Review and Biomechanical Study of the Invasive and Non-Invasive Methods and Their Influence on Knee Joint Loading
Rheumato, Vol. 5, Pages 8: Unlocking the Secrets of Knee Joint Unloading: A Systematic Review and Biomechanical Study of the
The Lancet
[Comment] The brain as a window into rheumatoid arthritis stratified medicine?
TNF inhibitors have transformed outcomes for many, but not all, people with rheumatoid arthritis. Their approval in the late 1990s
Rheumatology
Biomarkers in juvenile idiopathic arthritis: towards precision diagnosis and personalized therapy?
Purpose to review Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in children, characterized by persistent joint
The Lancet
[Comment] Polymyalgia rheumatica: killing them softly
Polymyalgia rheumatica has long been neglected, especially when it comes to pharmaceutical development: but why? In 2025, polymyalgia rheumatica should
Rheumato
Rheumato, Vol. 5, Pages 7: Two Cases of Statin-Induced Immune-Mediated Necrotizing Myopathy: A Rare Side Effect of Statins
Rheumato, Vol. 5, Pages 7: Two Cases of Statin-Induced Immune-Mediated Necrotizing Myopathy: A Rare Side Effect of Statins Rheumato doi:
NEJM
A Phase 3 Trial of Inebilizumab in Generalized Myasthenia Gravis
In adults with myasthenia gravis, treatment with intravenous inebilizumab, a CD19-specific monoclonal antibody, significantly improved function and reduced disease severity
NEJM
Unruptured Intracranial Aneurysms
Intracranial aneurysms are common, and the risk of rupture is influenced by size, location, morphology, and factors such as hypertension,
NEJM
Myasthenia Gravis — Redemption for B-Cell Depletion
Myasthenia gravis, an immune-mediated neurologic disorder, has for the past century been treated effectively with various immunotherapies, ranging from thymectomy
NEJM
Progress through Persistence — Turning the Page in Pulmonary Fibrosis Clinical Trials
The field of pulmonary fibrosis has come a long way in the past 25 years, with the approach to patient
NEJM
Case 16-2025: A 34-Year-Old Man with a Nasopharyngeal Mass
A 34-year-old man was admitted to the hospital because of left ear pain with hearing loss and facial droop on
Rheumatology
Update on streptococcal-associated rheumatic disease
Purpose of review This review provides a comprehensive perspective on poststreptococcal rheumatic manifestations in pediatric patients by integrating recent updates
JCR
Evaluation of Factors Associated With Uveitis Onset Timing in Oligoarticular Juvenile Idiopathic Arthritis
Objective To evaluate the timing of uveitis onset in patients with oligoarticular juvenile idiopathic arthritis (oJIA) and to identify clinical
NEJM
A Phase 3 Trial of Upadacitinib for Giant-Cell Arteritis
In this randomized, placebo-controlled trial involving patients with giant-cell arteritis, the oral Janus kinase inhibitor upadacitinib (15 mg) significantly improved
The Lancet
[Comment] One step closer to predicting autoimmune congenital heart block?
Autoimmune congenital heart block occurs in around 1–2% of anti-Sjögren’s syndrome-related antigen A (SSA)/Ro antibody-positive pregnancies.1 Despite the rarity of
Rheumatology
Evolution of the axial spondyloarthritis disease activity score and uptake in clinical practice
Purpose of review This review outlines the development of the axial spondyloarthritis disease activity score (ASDAS) as a composite index
Rheumato
Rheumato, Vol. 5, Pages 6: Comparison of Hip Abductor Muscle Composition and Its Age-Related Alterations Between Female Patients with Unilateral and Bilateral Osteoarthritis of the Hip
Rheumato, Vol. 5, Pages 6: Comparison of Hip Abductor Muscle Composition and Its Age-Related Alterations Between Female Patients with Unilateral
Rheumatology
Pathogenesis of juvenile idiopathic arthritis
Purpose of review To provide an overview of the most recent updates in the pathogenesis of juvenile idiopathic arthritis (JIA).
JCR
Interpretable Machine Learning for Predicting Anterior Uveitis in Axial Spondyloarthritis
Background Axial spondyloarthritis (axSpA) is a chronic inflammatory disease primarily affecting the spine and sacroiliac joints, with anterior uveitis (AU)
Rheumato
Rheumato, Vol. 5, Pages 5: Hemophilic Arthropathy—Pathophysiology and Advances in Treatment
Rheumato, Vol. 5, Pages 5: Hemophilic Arthropathy—Pathophysiology and Advances in Treatment Rheumato doi: 10.3390/rheumato5020005 Authors: Katarina Kovač Ivan Ljudevit Caktaš
JCR
Moving the ACR’s Reproductive Health Guidelines Into Practice: A Quantitative and Qualitative Assessment of a Novel Reproductive Rheumatology ECHO
Background Project ECHO (Extension for Community Healthcare Outcomes) links experts with community providers through video teleconferences that include both didactics
JCR
Comparative Efficacy and Safety of Different Regimens of Current JAK Inhibitors in Psoriatic Arthritis: A Network Meta-analysis
Background Janus kinase (JAK) inhibitors have been approved for treating psoriatic arthritis (PsA); however, the comparative efficacy of different JAK
JCR
Snapshot of a Decade: Idiopathic Inflammatory Myopathies in Chile—A 10-Year Short Report
Background Idiopathic inflammatory myopathies (IIMs) are rare autoimmune diseases with limited epidemiological data from Latin America. Objective To characterize IIMs
JCR
The Impact of Social Inequities on Presentation of Juvenile-Onset Systemic Lupus Erythematosus at a Large Tertiary Center
Objective The prevalence of juvenile-onset systemic lupus erythematosus (JSLE) differs by race/ethnicity with environmental, genetic, and social factors implicated in
JCR
Outcomes in Mexican Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis With Kidney Involvement
Background/Objective This study assessed the outcomes of patients with antineutrophil cytoplasm antibody–associated vasculitis glomerulonephritis (AAV-GN). Methods This historical cohort study