Objective The therapeutic effects of telitacicept combined with standard of care (SoC) in childhood-onset systemic lupus erythematosus (cSLE) remain unclear. […]
Arthritis &Rheumatology, EarlyView.
Objective Deficiency of adenosine deaminase 2 (DADA2) is a monogenic autoinflammatory disease manifested as polyarteritis nodosa, stroke, and bone marrow
Objective To explore whether biological levels of specific per- and polyfluoroalkyl substances (PFAS) and a mixture of PFAS – reflecting
Objective To develop evidence-based criteria to classify SURF patients. Methods 112 SURF patients followed in a single tertiary referral center
Abstracts Objective To weigh higher-dose HCQ (>=400 mg/d) and lower-dose HCQ (<400 mg/d) for effectiveness and safety among patients with
Objective International criteria for antiphospholipid syndrome (APS) include lupus anticoagulant (LA), anticardiolipin (aCL) IgG and IgM, and anti–β2-glycoprotein I (β2GPI)
Objective Caspase-4/5/11–mediated noncanonical pyroptosis emerges as a contributing factor in immune responses under pathologic conditions. However, its precise role in
Objective High intensity conditioning autologous hematopoietic stem cell transplantation (AHSCT) is standard of care for patients with advanced SSc. The
Objective To determine risk factors for relapse of ANCA-associated vasculitis (AAV) after re-induction of remission with rituximab and discontinuation of
Objective Mitochondria are organelles with a hypomethylated circular genome. Mitochondrial DNA (mtDNA) in the systemic circulation has been implicated in
Objective To evaluate the prognostic utility of circulating Interleukin-18 (IL-18) levels in predicting disease activity, macrophage activation syndrome (MAS), and
Objective Antiphospholipid syndrome (APS) is a thrombo-inflammatory disorder characterized by clinical and mechanistic heterogeneity that complicates early diagnosis and hinders
Arthritis &Rheumatology, Accepted Article.
Objective This study aimed to investigate the mechanisms of immune dysregulation in a pediatric patient with monogenic lupus driven by
Arthritis &Rheumatology, Accepted Article.
Arthritis &Rheumatology, Accepted Article.
Background Using hydroxychloroquine (HCQ) dose of 5 mg/kg/day in systemic lupus erythematosus (SLE) is associated with a higher risk of
Objective Polymyalgia rheumatica (PMR) is an age-related inflammatory disease with shoulder/hip girdle involvement. Magnetic resonance imaging (MRI) reveals extracapsular/entheseal soft
Arthritis &Rheumatology, EarlyView.
Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc), with high mortality and morbidity. Recent clinical studies
Objective The optimal treatment strategy for rheumatoid arthritis–associated interstitial lung disease (RA-ILD) remains uncertain, and direct comparative data between biologics
Background Transition from long-term denosumab to PTH-analogs or romosozumab might expose patients to the risk of the so-called rebound phenomenon.
Objective We evaluated serious infection risk in offspring exposed to tumour necrosis factor inhibitors (TNFi) in utero, separated by TNFi
Background ATP is released from platelets through both degranulation and pannexin-1 (PANX1) channels. ATP then activates P2X receptors to amplify
Objective To investigate the clinical characteristics, renal pathology treatment responses, and renal outcomes of lupus nephritis (LN) patients with different
Objectives Rheumatoid arthritis (RA) is a systemic chronic disabling autoimmune disease with high autoantibody production. However, approximately 1/3 of RA
