Molecular mechanisms for direct sensing of virus-like antigens by B cells
Int Immunol. 2025 Aug 30:dxaf052. doi: 10.1093/intimm/dxaf052. Online ahead of print. ABSTRACT Particulate antigens (Ags) such as viruses can often […]
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Vaccine adjuvants as stand-alone immunoprophylaxis in strategies for 100-day rapid responses to future pandemics
Int Immunol. 2025 Aug 30:dxaf053. doi: 10.1093/intimm/dxaf053. Online ahead of print. ABSTRACT The COVID-19 pandemic accelerated vaccinology progress, driving rapid
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Pemafibrate treatment produces antidepressant-like effects in CUMS and CRS models through activation of hippocampal PPARa and BDNF signaling
Int J Neuropsychopharmacol. 2025 Aug 30:pyaf063. doi: 10.1093/ijnp/pyaf063. Online ahead of print. ABSTRACT BACKGROUND: It is well established that peroxisome
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Exploring potential associations and biomarkers linked polycystic ovarian syndrome with atherosclerosis via comprehensive bioinformatics analysis, machine learning, and animal experiments
Funct Integr Genomics. 2025 Aug 30;25(1):181. doi: 10.1007/s10142-025-01686-y. ABSTRACT Polycystic ovary syndrome (PCOS), a common endocrine condition affecting multiple systems,
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Psychosocial and quality of life assessment in kidney transplant recipients: a focus on anxiety, depression, and clinical correlates
BMC Nephrol. 2025 Aug 29;26(1):501. doi: 10.1186/s12882-025-04418-3. NO ABSTRACT PMID:40883678 | DOI:10.1186/s12882-025-04418-3
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Exploring the therapeutic potential of MSC-derived secretomes in neonatal care: focus on BPD and NEC
Stem Cell Res Ther. 2025 Aug 29;16(1):476. doi: 10.1186/s13287-025-04616-8. NO ABSTRACT PMID:40883791 | DOI:10.1186/s13287-025-04616-8
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Pyrin inflammasome-driven erosive arthritis caused by unprenylated RHO GTPase signaling
EMBO Mol Med. 2025 Aug 29. doi: 10.1038/s44321-025-00298-0. Online ahead of print. ABSTRACT Geranylgeranyl pyrophosphate, a non-sterol intermediate of the
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Split vs single-dose oral methotrexate in rheumatoid arthritis: a randomized controlled trial (SMART study)
Clin Rheumatol. 2025 Aug 29. doi: 10.1007/s10067-025-07646-y. Online ahead of print. ABSTRACT OBJECTIVE: Pharmacokinetic evidence suggests split dose of oral
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Dysfunctional mitochondria in ageing T cells: a perspective on mitochondrial quality control mechanisms
EMBO Rep. 2025 Aug 29. doi: 10.1038/s44319-025-00536-z. Online ahead of print. ABSTRACT Dysfunctional mitochondria are a hallmark of T cell
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Macrophage-derived VISTA engages with LRIG1 and hinders gut epithelial repair in colitis
Cell Mol Immunol. 2025 Aug 29. doi: 10.1038/s41423-025-01338-y. Online ahead of print. ABSTRACT Disruption of the intestinal epithelial barrier and
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Harnessing an integrated glyco-nanovaccine technology for enhanced cancer immunotherapy
Commun Med (Lond). 2025 Aug 29;5(1):378. doi: 10.1038/s43856-025-01102-3. ABSTRACT BACKGROUND: Cancer immunotherapy, particularly using immune checkpoint inhibitors, has revolutionized cancer
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ADAPT-3D:accelerated deep adaptable processing of tissue for 3-dimensional fluorescence tissue imaging for research and clinical settings
Sci Rep. 2025 Aug 29;15(1):31841. doi: 10.1038/s41598-025-16766-z. ABSTRACT Light sheet microscopy and preparative clearing methods that improve light penetration in
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Treat-To-Target: Emergence of Second-Generation CD40L Inhibitors for Treatment of SLE-Identifying Beneficial Patient Candidates for CD40L Inhibitors in a Cross-Sectional SLE Cohort
Scand J Immunol. 2025 Sep;102(3):e70050. doi: 10.1111/sji.70050. ABSTRACT Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease characterised by heterogeneous
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The number of central nervous system-driven symptoms predicts subsequent chronic primary pain. Response to Br J Anaesth 2025; 135: 493-4 and 135: 495-6
Br J Anaesth. 2025 Aug 28:S0007-0912(25)00527-6. doi: 10.1016/j.bja.2025.07.074. Online ahead of print. NO ABSTRACT PMID:40883207 | DOI:10.1016/j.bja.2025.07.074
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Transcriptome analysis of unmedicated heterozygous familial Mediterranean fever patients reveals a type I interferon signature driving increasing Pyrin expression
Ann Rheum Dis. 2025 Aug 28:S0003-4967(25)04300-6. doi: 10.1016/j.ard.2025.08.001. Online ahead of print. ABSTRACT OBJECTIVES: Familial Mediterranean fever (FMF) is traditionally
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Podocyte infolding glomerulopathy: Clinical insights from two case studies in Malaysia
Malays J Pathol. 2025 Aug;47(2):301-308. ABSTRACT INTRODUCTION: Podocyte infolding glomerulopathy (PIG) is a rare glomerular disorder characterised by the infolding
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The number of central nervous system-driven symptoms predicts subsequent chronic primary pain. Response to Br J Anaesth 2025; 135: 305-8
Br J Anaesth. 2025 Aug 28:S0007-0912(25)00528-8. doi: 10.1016/j.bja.2025.07.075. Online ahead of print. NO ABSTRACT PMID:40883205 | DOI:10.1016/j.bja.2025.07.075
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Associated factors to health-related quality of life in anti-neutrophil cytoplasmic antibodies-associated vasculitis patients: Data from the Almenara Vasculitis Cohort
Reumatol Clin (Engl Ed). 2025 Aug 28:501942. doi: 10.1016/j.reumae.2025.501942. Online ahead of print. ABSTRACT OBJECTIVE: To determine the factors associated
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Interaction of ALDH2 and ALDH1A single-nucleotide polymorphisms with alcohol consumption and impact on osteoporosis risk
J Formos Med Assoc. 2025 Aug 28:S0929-6646(25)00459-0. doi: 10.1016/j.jfma.2025.08.040. Online ahead of print. ABSTRACT BACKGROUND: Osteoporosis is a systemic bone
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A Clinical Case Report of Deficiency of Adenosine Deaminase 2 Syndrome (DADA 2) Presenting as a Brachial Artery Aneurysm
Mediterr J Rheumatol. 2025 Oct 23;36(1):136-139. doi: 10.31138/mjr.120324.dai. eCollection 2025 Mar. ABSTRACT INTRODUCTION: Deficiency of adenosine deaminase 2 (DADA 2)
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Altered immune responses to mRNA vaccination against SARS-COV-2 are characterized by an impaired cross-talk between humoral and T-cellular immune compartments in patients with hematologic diseases
Vaccine. 2025 Aug 28;63:127666. doi: 10.1016/j.vaccine.2025.127666. Online ahead of print. ABSTRACT BACKGROUND: Patients with hematologic diseases frequently develop insufficient humoral
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Preexisting ulcerative colitis increases the risk of immune-related colitis and predicts divergent survival outcomes in gastrointestinal cancer patients treated with immune checkpoint inhibitors
Front Immunol. 2025 Aug 13;16:1627680. doi: 10.3389/fimmu.2025.1627680. eCollection 2025. ABSTRACT BACKGROUND: The risk of immune-related colitis (IRC) and efficacy of
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Advances in fertility preservation and pregnancy care for transplant patients
World J Transplant. 2025 Sep 18;15(3):103958. doi: 10.5500/wjt.v15.i3.103958. ABSTRACT Fertility preservation and pregnancymanagement are critical considerations for patients undergoing organtransplantation.
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Mass closure vs. layer-by-layer closure of transverse laparotomy in children: a randomized trial with ultrasound and elastography outcomes
Front Pediatr. 2025 Aug 13;13:1655851. doi: 10.3389/fped.2025.1655851. eCollection 2025. ABSTRACT BACKGROUND: transverse laparotomy incision presents a common and widely used
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Association of pro-inflammatory and anti-inflammatory cytokine polymorphisms with COVID-19 severity in unvaccinated patients
Front Immunol. 2025 Aug 13;16:1641285. doi: 10.3389/fimmu.2025.1641285. eCollection 2025. ABSTRACT BACKGROUND: Cytokines and chemokines are essential for establishing an appropriate
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CAR-T therapy: pioneering a new era in the treatment of autoimmune diseases
Front Immunol. 2025 Aug 13;16:1625166. doi: 10.3389/fimmu.2025.1625166. eCollection 2025. ABSTRACT CAR-T therapy, an innovative immunotherapeutic approach, genetically modifies T cells
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Pulmonary Aspergilloma in a Non-adherent Systemic Lupus Erythematosus Patient Receiving Long-Term Immunosuppression: A Report of a Rare Case
Cureus. 2025 Jul 28;17(7):e88925. doi: 10.7759/cureus.88925. eCollection 2025 Jul. ABSTRACT Pulmonary aspergilloma is an uncommon but potentially life-threatening condition that