Lupus, lupus nephritis may be part of ‘overlapping spectrum’
HUNTINGTON BEACH, Calif. — Non-nephritis lupus and lupus nephritis may actually be part of a spectrum of diseases rather than […]
Rheumatology
Wiley
Pharmacodynamic Effects of Litifilimab in Lupus in a Randomized, Placebo‐Controlled Phase 2 Study: Rapid and Sustained Reductions in Type I Interferon‐Associated Gene Expression and Cytokines
Objective The pharmacodynamic effects of litifilimab on type I interferon (IFN) response and correlations with clinical outcomes were investigated in
PubMed
Breastfeeding on ART and a closer look at drug transfer to HIV-exposed uninfected infants
Sci Rep. 2025 Sep 18;15(1):32612. doi: 10.1038/s41598-025-20259-4. ABSTRACT Adherence to antiretroviral therapy (ART) and maintaining an undetectable maternal HIV viral
PubMed
Stabilizing a mammalian RNA thermometer confers neuroprotection in subarachnoid hemorrhage
Nat Commun. 2025 Sep 18;16(1):8319. doi: 10.1038/s41467-025-63911-3. ABSTRACT Mammals tightly regulate their core body temperature, yet how cells sense and
PubMed
Infographic: landmark trials in Neuro-Ophthalmology-results of the phase II idiopathic intracranial hypertension drug trial
Eye (Lond). 2025 Sep 18. doi: 10.1038/s41433-025-03973-1. Online ahead of print. NO ABSTRACT PMID:40968152 | DOI:10.1038/s41433-025-03973-1
PubMed
Clinical Practice of Treatment Switch in Transplant-eligible Patients with Multiple Myeloma: An Exploratory Retrospective Analysis
Intern Med. 2025 Sep 18. doi: 10.2169/internalmedicine.5894-25. Online ahead of print. ABSTRACT Objective In the real-world clinical setting of transplant-eligible
PubMed
Setting a vision for British Society of Gastroenterology guidelines: embracing innovation while preserving methodological excellence and clinical utility
Gut. 2025 Sep 18:gutjnl-2025-336942. doi: 10.1136/gutjnl-2025-336942. Online ahead of print. NO ABSTRACT PMID:40967831 | DOI:10.1136/gutjnl-2025-336942
PubMed
Virtual cutting-based morphological differences in osteoarthritic and healthy knees: Implications for total knee arthroplasty prosthesis design
Chin J Traumatol. 2025 Sep 9:S1008-1275(25)00111-7. doi: 10.1016/j.cjtee.2025.08.003. Online ahead of print. ABSTRACT PURPOSE: End-stage knee osteoarthritis (OA) patients are
PubMed
Tocilizumab and electrolyte imbalance: severe hypokalaemia leading to paralysis
BMJ Case Rep. 2025 Sep 17;18(9):e266110. doi: 10.1136/bcr-2025-266110. ABSTRACT Tocilizumab, an interleukin-6 (IL-6) receptor antagonist, is widely used for inflammatory
PubMed
Macrotroponin as a cause of falsely elevated cardiac troponin in systemic sclerosis
BMJ Case Rep. 2025 Sep 17;18(9):e266536. doi: 10.1136/bcr-2025-266536. ABSTRACT This case report discusses a patient in his late 30s with
PubMed
Unilateral Forearm Lymphoedema as a Rare Extra-Articular Manifestation of Chronic Tophaceous Gout
Joint Bone Spine. 2025 Sep 16:105969. doi: 10.1016/j.jbspin.2025.105969. Online ahead of print. NO ABSTRACT PMID:40967335 | DOI:10.1016/j.jbspin.2025.105969
PubMed
The global prevalence of depression and anxiety among fibromyalgia patients: A systematic review and meta-analysis
J Affect Disord. 2025 Sep 16:120340. doi: 10.1016/j.jad.2025.120340. Online ahead of print. ABSTRACT BACKGROUND: Fibromyalgia syndrome (FM) is a prevalent
PubMed
The double-edged sword role of copper in rheumatoid arthritis: Mechanisms, therapeutics, and challenges
J Autoimmun. 2025 Sep 17;157:103484. doi: 10.1016/j.jaut.2025.103484. Online ahead of print. ABSTRACT Rheumatoid arthritis (RA) is a chronic systemic autoimmune
PubMed
From toxicity assessment to adaptive safety care: implementing comprehensive fast-track safety evaluation for anticancer drug development
ESMO Open. 2025 Sep 17;10(10):105796. doi: 10.1016/j.esmoop.2025.105796. Online ahead of print. ABSTRACT BACKGROUND: The conventional drug development pathway in oncology,
PubMed
Cell-free DNA as a complementary marker of therapeutic futility in adenoid cystic carcinoma
Oral Oncol. 2025 Sep 17;169:107688. doi: 10.1016/j.oraloncology.2025.107688. Online ahead of print. ABSTRACT BACKGROUND: Adenoid cystic carcinoma (ACC) is a malignancy
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Modified lung ultrasound score to assess extent and prognosis in systemic autoimmune …
AbstractObjectives. Lung ultrasound (LUS) assesses lung lesion severity in systemic autoimmune rheumatic disease-associated interstitial lung …
RheumNow
Join us Sept 23 @ 7PM ET for the next Rheum to Breathe Journal Club! We’ll dive into two pivotal ILD studies: 📄 FI
Join us Sept 23 @ 7PM ET for the next Rheum to Breathe Journal Club! We’ll dive into two pivotal
PubMed
Early autoimmune signature in a young woman: palmar erythema, capillaroscopic abnormalities, and triple autoantibody positivity including anti-nucleosome
Clin Chem Lab Med. 2025 Sep 16. doi: 10.1515/cclm-2025-0798. Online ahead of print. NO ABSTRACT PMID:40966715 | DOI:10.1515/cclm-2025-0798
PubMed
Cutaneous Vasculitis as a Manifestation of Oropouche Fever: Case Report
Pediatr Infect Dis J. 2025 Sep 12. doi: 10.1097/INF.0000000000004997. Online ahead of print. NO ABSTRACT PMID:40966740 | DOI:10.1097/INF.0000000000004997
PubMed
Disparities in physician access for rheumatology, dermatology, and gastroenterology: a systematic review
Am J Manag Care. 2025 Sep 1;31(9):e270-e277. doi: 10.37765/ajmc.2025.89792. ABSTRACT OBJECTIVES: Substantial disparities in access to health care, including to
PubMed
Infraorbital Nerve Enlargement in a Patient with IgG4-related disease
Mod Rheumatol Case Rep. 2025 Sep 12:rxaf057. doi: 10.1093/mrcr/rxaf057. Online ahead of print. ABSTRACT IgG4-related disease (IgG4-RD) is a systemic
PubMed
Retraction of: Targeting mechanistic target of rapamycin complex 2 attenuates immunopathology in systemic lupus erythematosus
Rheumatology (Oxford). 2025 Sep 12:keaf391. doi: 10.1093/rheumatology/keaf391. Online ahead of print. NO ABSTRACT PMID:40966663 | DOI:10.1093/rheumatology/keaf391
PubMed
S100A9 promotes inflammasome-dependent autoinflammation by blocking the degradation of SYK tyrosine kinase
J Leukoc Biol. 2025 Sep 12:qiaf129. doi: 10.1093/jleuko/qiaf129. Online ahead of print. ABSTRACT Autoinflammatory diseases such as CAPS (Cryopyrin-Associated Periodic
PubMed
Intracranial invasion of granulomatous sinusitis: report of a rare case of granulomatosis with polyangiitis
Mod Rheumatol Case Rep. 2025 Sep 12:rxaf058. doi: 10.1093/mrcr/rxaf058. Online ahead of print. ABSTRACT The involvement of the central nervous
PubMed
Pharmacokinetics, Pharmacodynamics, and Immunogenicity of CM313 in Healthy Participants: An Open-Label/Double-Blind, Randomized, Placebo-Controlled Phase 1 Trial
Clin Transl Sci. 2025 Sep;18(9):e70334. doi: 10.1111/cts.70334. ABSTRACT CM313, a novel humanized anti-CD38 monoclonal antibody, has demonstrated therapeutic potential in
PubMed
Regulatory Effect and Mechanism of Tanshinone I on Cell Apoptosis in Steroid-Induced Osteonecrosis of the Femoral Head
Kaohsiung J Med Sci. 2025 Sep 18:e70086. doi: 10.1002/kjm2.70086. Online ahead of print. ABSTRACT Steroid-induced osteonecrosis of the femoral head
RheumNow
ILD and Mortality in Systemic Autoimmune Rheumatic Diseases Dr. Bryant England, Lincoln, NE, discusses interstitial lu
ILD and Mortality in Systemic Autoimmune Rheumatic Diseases Dr. Bryant England, Lincoln, NE, discusses interstitial lu https://pbs.twimg.com/profile_images/1915149062988271616/2m4z_QPt_normal.jpg john+RNV2@john… Thu, 09/18/2025